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What is the most effective malaria drug? For adults with severe malaria, artesunate should be the treatment of choice. The drug is more effective than quinine, is simple to administer, and is safe.
Will malaria come back? Yes, your symptoms can sometimes come back if you have either the P. ovale or P. vivax types of malaria, and you will receive further treatment. This reduces the chance of malaria coming back. If at any time you develop malaria symptoms again after being treated for it, contact your GP as soon as possible.
What is the mode of action for artesunate? The mechanisms of action of artesunate remains unclear and debatable. Artesunate is a prodrug that is rapidly converted to its active form dihydroartemisinin (DHA). This process involves hydrolysis of the 4-carbon ester group via plasma esterase enzyme.
How does malaria affect the human body? During this time, malaria parasites multiply in a person's liver before invading red blood cells in the bloodstream. As the disease progresses, a person's spleen and liver enlarge. Malaria may cause anemia or jaundice. In some severe cases, it attacks the brain and create neurological problems.
What is malaria treatment and prevention? Travellers to areas with malaria are usually advised to take preventative anti -malarial drugs. There is no vaccine to prevent human infection by this parasite. Personal protection and the environmental management of mosquitoes are important in preventing illness.
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