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We conducted a systematic literature review to describe the cardiovascular effects reported after overdose of 5 common AAPM: aripiprazole, olanzapine, quetiapine, risperidone, and ziprasidone.
We tested the following hypotheses: 1) brain structure abnormalities will be more extensive in neuropsychologically impaired psychosis patients; 2) psychosis patients with evidence of cognitive decline will demonstrate a loss of brain tissue (i.
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Background: Antipsychotic maintenance clinical trials consistently report benefits for patients treated with antipsychotics versus those receiving placebo.
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It is a core feature of autism that social interactions appear to be far less rewarding for autistic children compared to typically developing children.
We have not included their data into our analysis because the new analyses cover different periods from our analysis, use different criteria for inclusion, and give insufficient information for us to determine which cases we have already incorporated and which are new.
Background: Intrinsic functional brain networks derived from resting state functional MRI studies are viewed as promising constructs in studies of genetic underpinnings of schizophrenia (Meda et al.
Results: Compared to healthy controls, FE patients exhibited higher FW in the right SLF and bilaterally in the CB, and ILF, and no FAt differences.
Results: About 25% of the sample was exposed to EBV at age 4 years.
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Oise Hospital (Picardie area, France) a sample of 20 stabilized patients with schizophrenia according to DSM-IV-TR criteria and a sample of 20 healthy controls.
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This study aims to examine the effects of a working memory focused cognitive remediation therapy (CRT) on cognitive difficulties experienced by patients with psychosis.
These antipsychotics are often cheaper than newer counterparts, especially the generic versions, which can be an important consideration when long-term treatment is necessary.
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Conclusion: Using a higher-dimensional model of time-varying connectivity that has recently yielded strong and consistent evidence of reduced connectivity dynamism in SZ patients, we now present a more detailed picture of symptom effects.
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Behavior change starts with the identification of maladaptive behavior patterns and activities that increase anxiety, and cognitive behavioral therapy helps individuals change these patterns by identifying the irrational beliefs and fears that distort their thinking and provoke anxiety.
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Peak levels in prolactin occurred at week 4 (mean for boys 28.
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The goal of this study is to determine the effectiveness of the various programs within the Kennedy Krieger Family Center (KKFC) using data from a computerized clinical database.
Prevalence of hyperprolactinemia in schizophrenic patients treated with conventional antipsychotic medications or risperidone.
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Table 4 enumerates the incidence, rounded to the nearest percent, of treatment-emergent adverse reactions that occurred during acute therapy with intramuscular ziprasidone in 1% or more of patients.
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As is similar to anxiety or depression, the connection between these symptoms and schizophrenia is not understood.
Actions ranging from walking to reaching become inaccurate and difficult to control, resulting in poor functional movements.
The longitudinal trajectory of substance use was evaluated with linear mixed models.
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The ADOS-G is an observational measure used to "press" for socio-communicative behaviors that are often delayed, abnormal, or absent in kids with ASD.
Carbamazepine (Epitol, Tegretol, generic), a standard alternative antiseizure drug used for mood stabilizing, is usually the second anti-seizure medication of choice.
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The patent assigns exclusive legal right to the inventor or patent holder, and may include entities such as the drug brand name, trademark, product dosage form, ingredient formulation, or manufacturing process A patent usually expires 20 years from the date of filing, but can be variable based on many factors, including development of new formulations of the original chemical, and patent infringement litigation.
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Our group has focused on two peripheral biochemical markers, putatively related to schizophrenia (SCZ), S100B and BDNF.
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The weight gain associated with the use of lithium can range from 4 kg (8.
Most typical (first-generation) and some atypical (second-generation) antipsychotics raise serum prolactin acutely; after the initial rise, serum prolactin frequently declines gradually (months to years), and in some cases may return to normal, despite continued administration of the drug.
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Results: Factor B, a component of the alternative complement pathway, and C5b-9 protein levels were significantly increased in schizophrenia.
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Also of interest is whether symptom remission is related to functional competence.
Although atypical antipsychotic agents, such as olanzapine, quetiapine, and clozapine, have shown to increase prolactin level, this effect is minimal and short-lived.
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If, following the screening process or during a routine "well youngster" check-up, your youngster's doctor sees any of the possible indicators of ASD, further evaluation is indicated.
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SZ alone will show greater deficits in ER than SZ with substance use thus showing better social functioning.
This paper will focus on the issues that need to be addressed during drug development, strategies aimed at identifying this risk during early preclinical and clinical phases of drug development and the regulatory assessment of the potential risk, particularly the electrocardiographic data from the clinical trials.
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It may be possible to engage the patient in treatmentfrom the perspective of his or her concerns for secondary symptoms such as depression, anxiety, or insomnia, rather than from the perspective of the primary symptoms of psychosis.
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Neurotransmitters (chemical messengers in the brain) that may be associated with bipolar disorder include dopamine, serotonin, and norepinephrine.
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Results: Eighty-three (78%) participants completed the 12 months of treatment.
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To robustly interpret such findings it is essential to determine if prolonged treatment with antipsychotic medications to some degree contributes to these brain changes.
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The solution is testing by random relabeling, meaning development of a classifier by any preferred means and then scrupulously reenacting that development with randomly relabeled cases and controls.
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