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What drugs interact with levothyroxine? Drugs that Impair Levothyroxine Absorption A number of drugs have been shown to impair the absorption of levothyroxine ; these drugs include calcium carbonate, aluminum- containing antacids, sucralfate, iron supplements, cholestyramine, sevelamer, and, possibly, ciprofloxacin, raloxifene, and orlistat. What happens if hypothyroidism is left untreated? Hypothyroidism occurs when the thyroid gland does not produce enough hormones. If your thyroid hormone levels are too low, you may have fatigue, digestive problems, sensitivity to cold temperatures, and menstrual irregularities. If left untreated, though, hypothyroidism can lead to many complications. What are high TSH levels? High TSH levels can mean your thyroid is not making enough thyroid hormones, a condition called hypothyroidism. Low TSH levels can mean your thyroid is making too much of the hormones, a condition called hyperthyroidism. T4 thyroid hormone tests. Can a high TSH level be dangerous? There are clear effects of thyroid hormone on the heart. Some clinical studies have shown an increased risk of heart disease and death in patients with hypothyroidism, both mild and overt. Further, an association has been suggested between TSH levels near the upper limit of the normal range and death in some studies. How quickly can TSH levels change? In both tests, the blood is taken at the same time of day because TSH levels can fluctuate over the course of 24 hours. Subclinical hypothyroidism is diagnosed when both TSH readings are high but the thyroid hormone thyroxine is still within the normal range.
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